This dataset was published as Table 3 from Havird et al (2015). It contains a list of mostly invertebrate taxa and whether or not they possess known vertebrate cyclooxygenase functional domains and residues.
Notes:
- AA residue: based on sheep COX-1 numbering (GenBank accession# NP_001009476)
- Many features in Brachiopoda are unknown (?) due to an incomplete (20 %) sequence being the only representative from this phylum.
- Annelida excludes Sipuncula sequences.
- Cephalochordata: see Havird et al. (2008) for conservation of domains and residues in Cnidaria and other Chordata.
Related Reference: Havird, J.C., K. M. Kocot, P. M. Brannock, J. T. Cannon, D. S. Waits, D. A. Weese, S. R. Santos, K. M. Halanych. 2015. Reconstruction of cyclooxygenase evolution in animals suggests variable, lineage-specific prostaglandin synthesis pathways. Journal of Molecular Evolution. 80:193-208. DOI 10.1007/s00239-015-9670-3
Related Datasets:
Havird_2015_T1: NCBI accessions: COX and PXDN
Havird_2015_T2: NCBI accessions: MPO and PXDN
Halanych, K. M., Mahon, A. (2016) Conservation of known vertebrate cyclooxygenase functional domains and residues, from Havird et al (2015) J Mol Evol., Table 3 (Antarctic Inverts project). Biological and Chemical Oceanography Data Management Office (BCO-DMO). (Version ) Version Date 2016-12-27 [if applicable, indicate subset used]. http://lod.bco-dmo.org/id/dataset/671770 [access date]
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